[On sickle-anemia mutation protecting against malaria]
If this is such a great mutation, why do we have a national organization to help people who have it?
123 Christian Forums
[10/29/2005 12:00:00 ]
Fundie Index: 3
Here, it's simple, the shape of the cells protects against malaria, but it can also be detrimental to health, but not as much as fucking malaria
10/29/2005 3:14:55 PM
It's evolutionary pressure from both sides, malaria is a problem and so is sickle - cell anemia, but the latter protects against the former, which is why it survived.
10/29/2005 6:32:12 PM
It's great for people who live in Africa. Sucks if you get two copies of the sickle-cell allele, but if you get only one you're not only immune to malaria but also don't get any significant symptoms of sickle-cell (unless you live at high altitudes).
Which might explain why blacks get sickle-cell far more often than whites do, for that matter ... heterozygotes are strongly favored in malaria-infested areas because people with \"normal\" genes die from malaria and people with two sickle-cell alleles die from sickle-cell. No such selective advantage exists in the US (or Europe).
If \"The Truth\" is so obvious, why do you need a book to push your ideas at people?
10/31/2005 7:44:34 PM
Darwin's Lil Girl
Because only one copy of the gene is nessesary for protection against malaria. Two gives you the desease.
Because ONE copy of the gene is protective against malaria. People with sickle cell disease have 2 copies. The fitness benefits of protection against malaria in the hetrozygotes outweighs the fitness cost of the disease in the homozygous recessive individuals. Selection works on genes, not on individuals.
Because the benefit of having protection against Malaria far outweighed the impact of the anemia it can cause.
I have no idea why I even bothered explaining.
Why are people this stupid given food?
10/3/2011 10:32:51 PM
Because it triggers other problems like bad oxygenation. This mutation, is not great at all, and the malaria protection is just a side effect.